Quantum of Solace continues one hour after the events of Casino Royale with Bond driving from Lake Garda to Siena, Italy — with the captured Mr White in the boot of his car — when he is attacked by chasing henchmen. After evading his pursuers, Bond and M interrogate White regarding his organisation, Quantum. M's trusted bodyguard Craig Mitchell turns traitor — allowing White to escape — so Bond chases Mitchell across Siena and kills him. Through forensic investigations involving tracked banknotes, Bond heads to Haiti to find Mitchell's contact, Edmund Slate, and kills him. He then poses as him, learning Slate was sent to kill Camille Montes at the behest of her partner, Dominic Greene, the ruthless chairman of Greene Planet and a member of Quantum. Bond pursues her by motorbike and watches her meet with Greene, learning the businessman is helping General Medrano — who murdered Camille's family — to stage a coup d'état in Bolivia in exchange for a seemingly barren piece of desert land. Quantum of Solace is scheduled to be released in the United States on November 14, 2008.

Madagascar: Back 2 Africa is scheduled to be released in the United States on November 6, 2008.

In Soul Men, two former backup soul singers, Louis (Samuel L. Jackson) and Floyd (Bernie Mac) who have not spoken to each other in 20 years reluctantly agree to travel across the country together to a reunion concert to honor their recently deceased lead singer (played by John Legend). Cleo (Sharon Leal), a beautiful young woman who is believed to be Floyd's daughter, accompanies them as a new singer.

Soul Men is scheduled to be released in the United States on November 6, 2008.

House is scheduled to be released in the United States on November 6, 2008.

In Repo! The Genetic Opera, an epidemic of organ failures devastates the planet. Panic erupts and scientists feverishly make plans for a massive organ harvest. Out of the tragedy, GeneCo, a multi-billion dollar biotech company, emerges. GeneCo provides organ transplantation for a profit. In addition to financing options, GeneCo reserves the right to implement default remedies, including repossession. For those who can't keep up with their organ payments, collection is the responsibility of "organ repo men", skilled assassins contracted by GeneCo, ordered to recover GeneCo's property by any means necessary.

At the heart of the story is Shilo Wallace (Alexa Vega), a 17 year-old girl with a rare blood disease. She has been kept locked up and protected in her house, where she is guarded from the outside world by her father, Nathan Wallace (Anthony Head). While Shilo struggles with her wish to leave the house and experience the outside world, Nathan struggles with his secret job as the Repo Man, and more specifically, his next target, a woman named Blind Mag (Sarah Brightman). Blind Mag, an opera singer, was a friend of Nathan's now-deceased wife, and is Shilo's godmother.

The Largo family, consisting of GeneCo president Rotti (Paul Sorvino), his daughter Amber (Paris Hilton), and his two sons Luigi and Pavi (Bill Moseley and Nivek Ogre, respectively), have their own plans. Rotti is dying, and the three siblings bicker and fight about who is to take the role as head of GeneCo. But, disappointed with his own children, Rotti takes an interest in Shilo.

The stories intertwine and merge at the GeneCo opera.

Repo! The Genetic Opera is scheduled to be released in the United States on November 6, 2008.