Splice is a 2010 science
fiction film directed by
Vincenzo Natali and starring
Adrien Brody and
Sarah Polley, who portray two young scientists and lovers who
begin involving human DNA in their splicing of animal genes.
Superstar genetic engineers Clive (Brody) and Elsa (Polley) achieve
fame by successfully splicing together the DNA of different animals,
to create incredible new hybrids. Now they want to use human DNA in
a hybrid that could revolutionize science and medicine. But when the
pharmaceutical company that funds their research forbids it, Clive
and Elsa secretly conduct their own experiments in the pursuit of
even greater scientific discovery. They secretly blend human DNA
with their creations, ignoring their society's ethical and legal
boundaries. The scientists name their creature "Dren", a creature
that exhibits uncommon intelligence and an array of unexpected
physical developments. And though, at first, Dren exceeds their
wildest dreams, she begins to grow and learn at an accelerated
rate—and threatens to become their worst nightmare. The two must
come to terms with their decision as their creature quickly develops
into a deadly, winged humanoid-chimera.
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